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Endometrial Stromal Tumors
The cause of development of Endometrial Stromal Tumor is related
to genetic abnormalities. The tumor is known to originate from the endometrial
stroma, in many cases. The gene mutations and chromosomal alterations are
specific to the subtype of EST.
Endometrial Stromal Tumors may be benign or malignant. Some
women may not show any signs and symptoms. In others, the signs and symptoms of
EST may include:
The
presence of a solitary, small or large tumor; the majority are between 5-10 cm
in size
Generally,
malignant tumors have poorly-defined boundaries; while, benign tumors are
mostly well-defined
Sensation
of pelvic mass or enlarged uterus
Most
of the tumors are located intramurally (i.e., found within the uterine walls)
In
some cases, polypoid tumors are observed
Heavy
or abnormal bleeding from the uterus and abdominal pain are both common
symptoms in women with EST
Signs
and symptoms may also occur from large-sized tumors causing compression of
adjoining uterine structures including frequent urination and lower back pain
Pain
during sexual intercourse
The diagnosis of Endometrial Stromal Tumor may
involve:
Complete
physical examination with thorough evaluation of medical history
Ultrasound
scan of the pelvis: It is a noninvasive procedure that uses high frequency
sound waves to produce real-time images
Abdominal
and pelvic CT scan: It is a noninvasive procedure that provides more details of
soft tissues, blood vessels, and internal organs
Pelvic
MRI scan: It is a noninvasive medical test that uses a powerful magnetic field
to produce images of soft tissues, bones, organs, and all other internal
structures of the abdomen and pelvis
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